By Gema Frühbeck (auth.), Kaiping Yang (eds.)
Since the e-book of the 1st variation, the options and experimental ways hired within the learn of adipose tissue have passed through radical enlargement and revision. In Adipose Tissue Protocols: moment Edition, numerous up-to-date chapters are mixed with many new contributions from across the world well-known specialists overlaying either traditional and cutting-edge methodologies in addition to entire animal, mobile and molecular methods that have emerged in or been prolonged to adipose tissue study over the last few years. As a quantity within the hugely sucessful Methods in Molecular Biology™ sequence, each one bankruptcy comprises an advent to its material, a listing of important fabrics, step by step, comfortably reproducible laboratory protocols, and a Notes part, which gives necessary suggestions and tips to protect opposed to power mishaps and pitfalls.
Cutting-edge and finished, Adipose Tissue Protocols: moment Edition is a necessary guide for rookies to this burgeoning region in addition to a priceless addition to the laboratories and places of work of more matured researchers.
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Extra info for Adipose Tissue Protocols
Int J Obes Relat Metab Disord 25:1431–1441 66. Moulin K, Truel N, Andre M, et al (2001) Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype. Biochem J 356:659–664 67. Gimble JM, Guilak F (2003) Differentiation potential of adipose derived adult stem (ADAS) cells. Curr Top Dev Biol 58:137–160 68. , Cousin B, et al (2004) Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives.
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1 Adipose Tissue in Obesity and Metabolic Disorders • catecholamines • EGF • flavonoids • GH • IL-1 • IL-6 • leptin • PDGF • PGF2αα • testosterone • TGF-β β α • TNF-α ANTI-ADIPOGENIC FACTORS 17 ADIPOGENIC FACTORS • adipogenin • angiotensin II • diet rich in saturat. fat • estrogens • glucocorticoids • IGF-1 • insulin • LIF • long-chain fatty acids • lysophasphatidic acid • MCSF • PAI-1 • PPARs • prolactin • retinoids • thyroid hormones Fig. 7 Main factors impinging on the regulation of adipogenesis The role of most adipokines has been extensively reviewed already (7–24,48–51), with research now concentrated on unravelling the potential mechanistic basis for the link between inflammation and insulin resistance, focusing, in particular, on some of the adipokines that have emerged more recently in the proinflammatory and metabolic syndrome scenario.
Adipose Tissue Protocols by Gema Frühbeck (auth.), Kaiping Yang (eds.)