Download PDF by J. B. West (auth.), T. H. Stanley, R. J. Sperry (eds.): Anesthesia and the Lung 1992

By J. B. West (auth.), T. H. Stanley, R. J. Sperry (eds.)

ISBN-10: 9401052085

ISBN-13: 9789401052085

ISBN-10: 9401127247

ISBN-13: 9789401127240

Anesthesia and the Lung 1992 provides fresh advances within the prognosis, pre-, intra-, and postoperative anesthetic administration of sufferers with lung ailment, proposing for pulmonary and non-pulmonary surgical procedure. It additionally bargains with ventilation-perfusion concerns, the lung as a metabolic organ, the consequences of anesthesia on pulmonary mechanics and pulmonary blood circulation. moreover, there are chapters that concentrate on hypoxia; neighborhood alterations within the lung; pulmonary surfactant; fresh advances within the realizing of pulmonary edema; excessive altitude affliction; anesthesia and the keep an eye on of respiring; fresh improvement in oximetry; instrumentation designed to degree pulmonary oxygen pressure, pO2 and pCO2 transcutaneously; differential lung air flow; reactive airlines; septic surprise; the grownup respiration misery syndrome and various points of ventilatory help.

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By J. B. West (auth.), T. H. Stanley, R. J. Sperry (eds.)

ISBN-10: 9401052085

ISBN-13: 9789401052085

ISBN-10: 9401127247

ISBN-13: 9789401127240

Anesthesia and the Lung 1992 provides fresh advances within the prognosis, pre-, intra-, and postoperative anesthetic administration of sufferers with lung ailment, proposing for pulmonary and non-pulmonary surgical procedure. It additionally bargains with ventilation-perfusion concerns, the lung as a metabolic organ, the consequences of anesthesia on pulmonary mechanics and pulmonary blood circulation. moreover, there are chapters that concentrate on hypoxia; neighborhood alterations within the lung; pulmonary surfactant; fresh advances within the realizing of pulmonary edema; excessive altitude affliction; anesthesia and the keep an eye on of respiring; fresh improvement in oximetry; instrumentation designed to degree pulmonary oxygen pressure, pO2 and pCO2 transcutaneously; differential lung air flow; reactive airlines; septic surprise; the grownup respiration misery syndrome and various points of ventilatory help.

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Extra resources for Anesthesia and the Lung 1992

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Lymphocytes are found free on the alveolar surface, scattered throughout the interstitium, and concentrated in specialized regions in the submucosa of proximal airways (called bronchus-associated lymphoid tissue). The relative proportions of the various lymphocyte subtypes recovered from the normal human lung by lavage is similar to that found in the blood. The cells are able to respond to mitogens, secrete lymphokines, and produce immunoglobulins when they are activated. The polymorphonuclear leukocyte (PMN), although not found as a resident cell in the normal lung parenchyma, is an extremely important effector cell in lung inflammation.

DIRECT INJURY TO LUNG PARENCHYMAL CELLS BY INHALED TOXINS; 02 TOXICITY Some materials are directly toxic to lung parenchymal cells if they gain access to the lower respiratory tract. Certain gases are particularly toxic to lung cells, including ammonia, chlorine, nitrogen dioxide, and oxygen in high concentrations. Highly soluble gases such as ammonia and chlorine cause major injury to cells of the proximal tracheobronchial epithelium with little of the gas usually reaching the alveoli, whereas less soluble gases such as 02 and N20 penetrate more deeply to the alveoli.

H. Stanley and R. J. ) , Anesthesia and the Lune 1992, 53-67. © 1992 KilMer Academic Publishers. 54 The material in this chapter is not encyclopedic, but will emphasize mechanisms that are currently thought to be important in a variety of different disease processes. OUTLINE OF CHAPTER A. B. C. D. E. Failure of normal lung defenses Direct injury by inhaled toxins: 02 toxicity as an example Enzyme-mediated destruction of alveolar walls: the concept of "protease-antiprotease imbalance" Injury caused by cellular and humoral mediators of inflammation 1.

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Anesthesia and the Lung 1992 by J. B. West (auth.), T. H. Stanley, R. J. Sperry (eds.)


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